[Biofizika] [Ebsa] Postdoctoral fellowship in Computational Biophysics

[Paolo Ruggerone]

News associated with biophysics - supported by the European Biophysical Societies' Association (EBSA) - www.ebsa.org/

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Post-doc Researcher in the Group of Computational Biophysics

The Group of Computational Biophysics at the Physics Department of the University of Cagliari is opening a two-years Post-doc position on timely problems related to multidrug bacterial resistance mediated by efflux systems (more info at www.dsf.unica.it/~paolo/). The position is within the framework of the IMI - ND4BB action (Innovative Medicine Initiative -New Drugs for Bad Bugs, see http://www.imi.europa.eu/content/translocation). The Group is also involved in a second project under the ITN-Marie Curie action (http://cordis.europa.eu/project/rcn/109792_it.html).

Tasks
? MD simulations with standard and biased techniques to study the interaction of specific compounds with bacterial efflux pumps.
? Evaluation of thermodynamics and kinetics parameters associated with the compound-efflux pump interactions.
? Molecular modelling of efflux pumps in their apo form and in complex with compounds.
? Interactions with all research partners of the multidisciplinary project.	

Requirements
? PhD in Physics, Chemistry, Bioinformatics, Computational biology, Pharmaceutical Chemistry, Biotechnology.
? Strong publication record in the field of molecular simulation/ molecular modelling.
? Experience in the use of most common molecular modelling/simulation packages (gromacs, amber, namd, modeller,..) and of methods to evaluate free energies.
? Desiderable experience in quantum chemistry methods and hybrid QM/MM codes.
? Fluent written and spoken English.	

We offer
? Fixed-term position (2 years).
? Dynamic and productive working environment.
? Interdisciplinary collaboration with world-leading international research groups including scientists of GlaxoSmithKlein, Sanofi-Aventis, Basilea Pharmaceutica Ltd.
? Travel support to participate to international conferences and workshops.	


Information on the position including a template of the application form will be available at the following link
http://dirpersonale.unica.it/concorsi/index.php?page=assegni&bando=599
The candidate should provide at least two reference letters.

For further information, please contact
Paolo Ruggerone
T: +390706754922
paolo.ruggerone at dsf.unica.it

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/------------------ooO-(_)-Ooo-----------------\
|                 Paolo Ruggerone                  |                
|               Dipartimento di Fisica             | 
|                Universit? di Cagliari              |
|               Cittadella Universitaria            |
|     S.P. Monserrato-Sestu Km 0.700     | 
|    I-09042 MONSERRATO (CA), Italy   |
|               tel +39 070 6754922               |
|               fax +39 070 6753191              |
|       paolo.ruggerone at dsf.unica.it         |
|                   skype: paolorug                   |
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