<html><body><div style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: #000000"><div><strong><span style="font-size: 12.0pt; font-family: 'Arial','sans-serif';" data-mce-style="font-size: 12.0pt; font-family: 'Arial','sans-serif';" lang="EN-GB"> Poštovani,</span></strong></div><div><span style="font-size: 12.0pt; font-family: 'Arial','sans-serif';" data-mce-style="font-size: 12.0pt; font-family: 'Arial','sans-serif';" lang="EN-GB"><br> <strong><span style="font-family: 'Arial','sans-serif';" data-mce-style="font-family: 'Arial','sans-serif';">podsjećamo Vas na <span style="color: red;" data-mce-style="color: red;">današnji</span> seminar na</span></strong></span><span style="font-size: 10.0pt; font-family: 'Arial','sans-serif';" data-mce-style="font-size: 10.0pt; font-family: 'Arial','sans-serif';" lang="EN-GB"> </span><strong><span style="font-size: 12.0pt; font-family: 'Arial','sans-serif';" data-mce-style="font-size: 12.0pt; font-family: 'Arial','sans-serif';" lang="EN-GB">Institutu za fiziku u <span style="color: red;" data-mce-style="color: red;">15:00 </span><span style="color: black;" data-mce-style="color: black;">sati:</span></span></strong></div><div style="color:#000;font-weight:normal;font-style:normal;text-decoration:none;font-family:Helvetica,Arial,sans-serif;font-size:12pt;" data-mce-style="color: #000; font-weight: normal; font-style: normal; text-decoration: none; font-family: Helvetica,Arial,sans-serif; font-size: 12pt;"><div><br></div><div style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: #000000" data-mce-style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: #000000;"><div style="color:#000;font-weight:normal;font-style:normal;text-decoration:none;font-family:Helvetica,Arial,sans-serif;font-size:12pt;" data-mce-style="color: #000; font-weight: normal; font-style: normal; text-decoration: none; font-family: Helvetica,Arial,sans-serif; font-size: 12pt;"><div style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: #000000" data-mce-style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: #000000;"><div style="color:#000;font-weight:normal;font-style:normal;text-decoration:none;font-family:Helvetica,Arial,sans-serif;font-size:12pt;" data-mce-style="color: #000; font-weight: normal; font-style: normal; text-decoration: none; font-family: Helvetica,Arial,sans-serif; font-size: 12pt;"><div style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: rgb(0, 0, 0); text-align: center;" data-mce-style="font-family: arial,helvetica,sans-serif; font-size: 12pt; color: #000000; text-align: center;"><p style="margin: 0px;" data-mce-style="margin: 0px;"><span lang="HR"> </span></p><p style="margin: 0px; text-align: center;" data-mce-style="margin: 0px; text-align: center;"><span lang="HR"><img src="cid:96a0879478ab2486466011d744bd9b41f3b5c969@zimbra" data-mce-src="cid:96a0879478ab2486466011d744bd9b41f3b5c969@zimbra" width="200"> <img src="cid:de0aa620b23ece4e88c650568cdd28db12d5950b@zimbra" data-mce-src="cid:de0aa620b23ece4e88c650568cdd28db12d5950b@zimbra" width="180"></span></p><p style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><span lang="HR"> </span></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><b><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" lang="HR"> </span></b></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><b><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" lang="HR">ZAJEDNIČKI SEMINAR </span></b></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><b><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" lang="HR">Hrvatskog biofizičkog društva i Instituta za fiziku</span></b></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><b><span style="font-family: 'Calibri','sans-serif';" data-mce-style="font-family: 'Calibri','sans-serif';" lang="HR"></span></b><b><span style="font-family: 'Calibri','sans-serif';" data-mce-style="font-family: 'Calibri','sans-serif';" lang="HR"><b><span style="font-size: 12.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 12.0pt; font-family: 'Calibri','sans-serif';">13. studenoga 2014. (četvrtak) </span></b><b><span style="font-size: 12.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 12.0pt; font-family: 'Calibri','sans-serif';">u 15:00 sati </span></b></span></b></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><span style="font-family: 'Calibri','sans-serif';" data-mce-style="font-family: 'Calibri','sans-serif';" lang="HR">Institut za fiziku, Bijenička cesta 46, predavaonica u III krilu</span></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><span style="font-family: 'Calibri','sans-serif';" data-mce-style="font-family: 'Calibri','sans-serif';" lang="HR"> </span><b><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" lang="HR"> <br></span></b></p><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><b><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" lang="HR">Danijel Grgičin</span></b></p><span style="font-size: 12.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 12.0pt; font-family: 'Calibri','sans-serif';">Institut za fiziku, Zagreb</span><br><p class="Default" style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" lang="HR"> </span></p><p style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><strong><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';"><b><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" lang="HR">Novi pristup izučavanju denaturacije DNK</span></b></span></strong></p><p style="text-align: center; margin: 0px;" data-mce-style="text-align: center; margin: 0px;" align="center"><strong><span style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 16.0pt; font-family: 'Calibri','sans-serif';"><br></span></strong></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-family: 'Calibri','sans-serif';" data-mce-style="font-family: 'Calibri','sans-serif';" lang="HR">U deoksiribonukleinskoj kiselini (DNK) živih organizama genetska informacija je pohranjena u konformaciji dvostruke uzvojnice (ds). Međutim, prepisivanje genetske informacije u svrhu izrade proteina ili u svrhu kopiranja genetske informacije se odvija na konformaciji jednostruke uzvojnice (ss). Efekt slaganja baza (eng. base stacking) i vodikove veze čuvaju DNK u ds konformaciji, dok repulzija fosfatnih grupa destabilizira DNK. Kada potonje prevlada DNK se denaturira u ss konformaciju. Od 1970.-tih se denaturacija DNA rutinski prati UV apsorbancijom. Ovdje izvještavamo o našem pristupu koji kombinacijom dielektrične spektroskopije i konduktometrije omogućava određivanje međusobne udaljenosti DNK lanaca, tj. de Gennesovu korelacijsku duljinu kao i broj protuiona kondenziranih na DNK. Udaljenost lanaca govori o njihovoj koncentraciji te može ukazivati na denaturaciju a važnost određivanja broja kondenziranih protuiona je u činjenici da oni neutraliziraju fosfatne grupe, tj. poznavanjem njihova udjela se može odrediti sila koja djeluje na fosfatne grupe i uzrokuje denaturaciju. </span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR"> </span></p><p style="margin: 0px;" data-mce-style="margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR">* * *</span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR"> </span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR">D. Grgičin, zn. novak na Institutu na fiziku od 2010, predstavlja svoj rad u području fizike polielektrolita:</span><span lang="PL"></span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" lang="FR">D. Grgičin (T. Vuletić, S. Tomić) et al. </span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';">Phys. Rev. E 88, 052703 (2013) - <i>Effect of magnesium ions on dielectric relaxation in semidilute DNA aqueous solutions</i></span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';">Phys. Rev. E 83, 041803 (2011) - <i>Manning free counterions fraction for a rod-like polyion – short DNA fragments in very low salt</i></span><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';"></span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" lang="EN-GB">Phys. </span><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif';">Rev. E 82, 011922 (2010) - <i>Structure and dynamics of hyaluronic acid semidilute solutions: a dielectric spectroscopy study</i></span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR">D. Grgičin je nedavno održao i predavanja na konferenciji <i>From Solid State to BioPhysics</i>, 7-14.06. 2014, Cavtat, i na školi <i>12<sup>th</sup> Greta Pifat Mrzljak International School of Biophysics</i>, 27.9.-6.10. 2014, Primošten.</span><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;"></span></p><p style="text-align: justify; margin: 0px;" data-mce-style="text-align: justify; margin: 0px;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR"><br></span></p><p style="margin: 0px; text-align: right;" data-mce-style="margin: 0px; text-align: right;"><span style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" data-mce-style="font-size: 11.0pt; font-family: 'Calibri','sans-serif'; color: black;" lang="HR">Voditelji seminara IF-a: Nikša Krstulović i Osor Barišić</span></p></div></div></div></div></div></div><div><br></div></div></body></html>