<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<!--[if !mso]><style>v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style><![endif]--><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-language:EN-US;}
h1
{mso-style-priority:9;
mso-style-link:"Heading 1 Char";
mso-margin-top-alt:auto;
margin-right:0cm;
mso-margin-bottom-alt:auto;
margin-left:0cm;
font-size:24.0pt;
font-family:"Times New Roman",serif;
font-weight:bold;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
span.EmailStyle18
{mso-style-type:personal-compose;
font-family:"Calibri",sans-serif;
color:windowtext;}
span.Heading1Char
{mso-style-name:"Heading 1 Char";
mso-style-priority:9;
mso-style-link:"Heading 1";
font-family:"Times New Roman",serif;
mso-fareast-language:EN-GB;
font-weight:bold;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:10.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-language:EN-US;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:72.0pt 72.0pt 72.0pt 72.0pt;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-GB" link="#0563C1" vlink="#954F72" style="word-wrap:break-word">
<div class="WordSection1">
<h1 style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif;font-weight:normal">Dear EBSA mailing list – please could you share the following postdoc opportunity. Thanks in advance<o:p></o:p></span></h1>
<h1 style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif;font-weight:normal">Andy<o:p></o:p></span></h1>
<h1 style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p> </o:p></span></h1>
<h1 style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif">Research Fellow in Chemical Biology<o:p></o:p></span></h1>
<p style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm;box-sizing: border-box">
<strong><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">Are you an ambitious researcher looking for your next challenge? Do you have an established background in chemical biology in its broadest sense? Do you want to further your career in one
of the UKs leading research intensive universities?</span></strong><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p></o:p></span></p>
<p style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm;box-sizing: border-box">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif">As Research Fellow in Chemical Biology you will join a BBSRC-funded team focused on developing and exploiting new tools to understand and perturb protein-protein interactions (PPIs) involving intrinsically
disordered regions. You will assist the Investigators in delivering this large research programme by focussing on the design and synthesis of small-molecule chemical probes for disease relevant PPIs, with considerable emphasis on targets in oncology.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm;box-sizing: border-box">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif">The post is associated with a major £5.4 million five-year collaborative research programme led by <a href="https://wilson.leeds.ac.uk/"><span style="color:#B31B1B">Professor Andy Wilson</span></a>,
funded by the <a href="https://bbsrc.ukri.org/" target="_blank"><span style="color:#B31B1B">Biotechnology and Biological Sciences Research Council (BBSRC)</span></a>, and bringing together the <a href="http://www.leeds.ac.uk/" target="_blank"><span style="color:#B31B1B">University
of Leeds</span></a>, the <a href="https://www.ox.ac.uk/"><span style="color:#B31B1B">University of Oxford</span></a>, and project partners, <a href="https://www.astrazeneca.co.uk/"><span style="color:#B31B1B">AstraZeneca</span></a> and <a href="https://www.lifearc.org/"><span style="color:#B31B1B">LifeArc</span></a>.
This large and diverse programme focuses on <em><span style="font-family:"Calibri",sans-serif">Deciphering the function of intrinsically disordered protein regions in a cellular context</span></em> using The Aurora A kinase (Aurora A) as a target. Aurora A
represents a key potential target for anticancer therapeutics development and plays a fundamental role in regulating cell division.The specific purposes of the role are to (i) develop reagents capable of inhibiting the interactions of Aurora A, (ii) use proteomics
methods to dissect the cellular interactome of Aurora A.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm;box-sizing: border-box">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif">You will be part of a large team based in <a href="https://wilson.leeds.ac.uk/"><span style="color:#B31B1B">The Wilson</span></a>, and <a href="https://wright.leeds.ac.uk/"><span style="color:#B31B1B">The
Wright</span></a> groups in the <a href="https://physicalsciences.leeds.ac.uk/info/4/school_of_chemistry"><span style="color:#B31B1B">School of Chemistry</span></a> and the <a href="http://www.astbury.leeds.ac.uk/research/facilities.php"><span style="color:#B31B1B">Astbury
Centre for Structural Molecular Biology</span></a> with access to a superb infrastructure for research in chemical biology, including synthetic laboratories, NMR equipment, X-ray crystallographic, mass spectrometry and biophysical techniques, together with
state of the art online resources.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm;box-sizing: border-box">
<span style="font-size:11.0pt;font-family:"Calibri",sans-serif">You will have a PhD (or have submitted your thesis prior to starting) in an area appropriate to the project, along with extensive knowledge of chemical proteomics and/or chemical probe development.<o:p></o:p></span></p>
<p class="MsoNormal" style="box-sizing: border-box"><b>Location:</b> Leeds - Main Campus<o:p></o:p></p>
<p class="MsoNormal"><b>Faculty/Service:</b> Faculty of Engineering & Physical Sciences<o:p></o:p></p>
<p class="MsoNormal"><b>School/Institute:</b> School of Chemistry<o:p></o:p></p>
<p class="MsoNormal"><b>Category:</b> Research<o:p></o:p></p>
<p class="MsoNormal"><b>Grade:</b> Grade 7<o:p></o:p></p>
<p class="MsoNormal"><b>Salary:</b> £33,797 to £40,322 p.a.<o:p></o:p></p>
<p class="MsoNormal"><b>Working Time: </b> 37.5 hours per week<o:p></o:p></p>
<p class="MsoNormal"><b>Post Type:</b> Full Time<o:p></o:p></p>
<p class="MsoNormal"><b>Contract Type: </b> Fixed Term (3 years due to grant funding)<o:p></o:p></p>
<p class="MsoNormal"><b>Closing Date: </b> Sunday 22 November 2020<o:p></o:p></p>
<p class="MsoNormal"><b>Interview Date:</b> To be confirmed<o:p></o:p></p>
<p class="MsoNormal"><b>Reference:</b> EPSCH1022<o:p></o:p></p>
<p class="MsoNormal"><b>Downloads:</b> <a href="https://jobs.leeds.ac.uk/Upload/vacancies/files/18783/EPSCH1022%20-Research%20Fellow%20in%20Chemical%20Biology.pdf" target="_blank"><span style="color:#AA8F6F;background:white">Candidate Brief</span></a><span style="font-size:13.5pt;color:#444444;background:white"> </span>
<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">You can apply online via: <span style="color:#444444;mso-fareast-language:EN-GB">
<a href="https://jobs.leeds.ac.uk/Vacancy.aspx?ref=EPSCH1022">https://jobs.leeds.ac.uk/Vacancy.aspx?ref=EPSCH1022</a>
</span><o:p></o:p></p>
<p style="mso-margin-top-alt:7.5pt;margin-right:0cm;margin-bottom:7.5pt;margin-left:0cm;background:white">
<strong><span lang="EN" style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black">To explore the post further or for any queries you may have, please contact:
</span></strong><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#444444"><a href="https://wilson.leeds.ac.uk/"><span style="color:#B31B1B">Professor Andrew J Wilson</span></a>, Professor of Organic Chemistry, School of Chemistry Tel: +44
(0)113 3431409 or email: <a href="mailto:a.j.wilson@leeds.ac.uk"><span style="color:#B31B1B">a.j.wilson@leeds.ac.uk</span></a> <o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Prof Andy Wilson</span><span style="font-family:"Times New Roman",serif;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Royal Society Leverhulme Trust Senior Research Fellow
</span><span style="font-family:"Times New Roman",serif;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Professor of Organic Chemistry
</span><span style="font-family:"Times New Roman",serif;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Room G.15</span><span style="font-family:"Times New Roman",serif;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">School of Chemistry and Astbury Centre for Structural Molecular Biology</span><span style="font-family:"Times New Roman",serif;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">University of Leeds</span><span style="font-family:"Times New Roman",serif;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Woodhouse Lane<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Leeds LS2 9JT<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">United Kingdom<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">A.J.Wilson@leeds.ac.uk <o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Office +44 (0)113 3431409<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Lab +44 (0)113 3436549 or 3436564<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Fax +44 (0)113 3436565<o:p></o:p></span></p>
<p class="MsoNormal"><a href="https://wilson.leeds.ac.uk/"><span style="color:#0563C1;mso-fareast-language:EN-GB">https://wilson.leeds.ac.uk/</span></a><span style="mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><a href="http://www.poppi.website/"><span style="color:#0563C1;mso-fareast-language:EN-GB">http://www.poppi.website/</span></a><span style="mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><a href="http://www.poppi.website/"><span style="color:#0563C1;mso-fareast-language:EN-GB;text-decoration:none"><img border="0" width="255" height="94" style="width:2.6597in;height:.9791in" id="Picture_x0020_1" src="cid:image002.png@01D6B6C1.009F6DC0"></span></a><span style="mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>