[Biofizika] Fwd: New PostDoc position on engineering an efficient resource recycling system in E.coli (ref. EN20160385FH)
Juraj Szavits Nossan
jszavits at staffmail.ed.ac.uk
Pon Stu 7 10:28:22 CET 2016
> Begin forwarded message:
>
> *From: *Guy-Bart Stan <g.stan at imperial.ac.uk
> <mailto:g.stan at imperial.ac.uk>>
> *Subject: **New PostDoc position on engineering an efficient resource
> recycling system in E.coli (ref. EN20160385FH)*
> *Date: *November 1, 2016 at 11:19:37 PM GMT+8
> *To: *undisclosed-recipients: ;
> *Resent-From: *Yizhi.Cai at ed.ac.uk <mailto:Yizhi.Cai at ed.ac.uk>
>
> Dear Colleagues,
>
> Could you please forward the following information to any excellent
> synthetic biology PostDoc interested in participating in the
> development of a *novel, fast and efficient resource recycling system
> for improving the performance of engineered cells*.
>
> _*Deadline for applications:*_ 27 November 2016 (midnight GMT)
>
> _*Brief description:*_
>
> The Department of Bioengineering (Stan Group,
> http://www.bg.ic.ac.uk/research/g.stan/group,
> http://www.imperial.ac.uk/people/g.stan) at Imperial College London is
> seeking to appoint an excellent, highly motivated and dynamic Research
> Associate to join the Centre for Synthetic Biology and Innovation
> (CSYNBI), on a fixed-term position to work on a novel and exciting
> *synthetic biology* project.
>
> The position will be based at the South Kensington Campus in the Stan
> Group, working closely with Dr Guy-Bart Stan, his research group and
> other members of CSYNBI on a project focused on the use and control of
> proteases in E. coli and the re-engineering of the trans-translation
> pathway to increase the turn-over/recycling of amino acids and thereby
> improve production yields of proteins. The successful candidate will
> design and implement a novel and *efficient synthetic resource
> recycling system* that will allow for any strain of a given bacterial
> host expressing a synthetic biology construct to a) sense the
> occurrence of wasteful sequestration of ribosomes and amino acids and
> b) automatically activate, in response, a synthetic recycling
> mechanism releasing these resources, thereby offering a novel way to
> increase protein production yields by simultaneously improving growth
> and protein production rates.
>
> We seek a highly motivated individual to fill this post, in possession
> of a PhD or equivalent in synthetic biology, molecular microbiology,
> systems biology, or cellular engineering with desired postdoctoral
> experience in a synthetic biology lab.
>
> The ideal candidate will have expertise in E. coli synthetic biology
> and microbial biology engineering, and in mathematical modelling and
> numerical simulations (deterministic and/or stochastic) of biological
> or biochemical systems. He or she will be proficient in designing and
> cloning genes using next generation cloning methods (e.g. Gibson,
> Golden Gate, BASIC, etc.) and in engineering of cellular systems.
> Experience with fluorescence-based measurement and analysis, FACS, and
> genetic engineering are essential. Expertise and/or experience with
> mathematical modelling (e.g. using Matlab) is highly desirable. The
> post is funded by the UK Engineering and Physical Science Research
> Council (EPSRC).
>
> _*For more details and to apply:*_
> https://www4.ad.ic.ac.uk/OA_HTML/OA.jsp?page=/oracle/apps/irc/candidateSelfService/webui/VisVacDispPG&akRegionApplicationId=821&transactionid=567147296&retainAM=Y&addBreadCrumb=S&p_svid=50158&p_spid=1809313&oapc=8&oas=yp_o6rMcrRp6ijY5Qa87iA
>
> If there is a problem with the above link, please go to
> https://www4.ad.ic.ac.uk/OA_HTML/IrcVisitor.jsp and search using
> *EN20160385FH* in the Keywords section to find the advert and how to apply
> --
> Dr Guy-Bart Stan, EPSRC Fellow, CEng, MIEEE, MIET
> Reader in Engineering Design for Synthetic Biology
> "Control Engineering Synthetic Biology" Group Leader
> Department of Bioengineering
> Imperial College London
> Personal Webpage:http://www.bg.ic.ac.uk/research/g.stan/
> Group Webpage:http://www.bg.ic.ac.uk/research/g.stan/group/
> Imperial Synthetic Biology webpage:http://www.imperial.ac.uk/synthetic-biology
> Office: +44 (0) 207 59 46375
> Fax: +44 (0) 207 59 49817
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